Being the son of Frankenstein's Monster and the Bride, Boy can't go out in public. That is, unless he wants to face the wrath of a torch-wielding mob. They all live in an enclave of monsters under Times Square, the humans blissfully unaware of their existence. Boy, however, has only interacted with the outside world through the Internet - not only that, he's a well-known hacking genius. But after one of his viruses go awry, Boy runs away from home and ends up meeting the granddaughters of Jekyll and Hyde, who introduce him to all the human world has to offer.